Management of malignant pleural effusions
نویسندگان
چکیده
Malignant pleural effusions (MPE) are a common occurrence in many advanced malignancies. They are a significant cause of morbidity and mortality; symptoms can be debilitating to patients and impair quality of life, especially as many of these patients are already functionally impaired by their underlying cancer and medical treatment. MPE generally represent advanced stage malignancy and the primary goal of therapy is palliation of symptoms. The purpose of this article is to review the therapeutic options available in the treatment of MPE and discuss clinical factors affecting management decision-making.
منابع مشابه
Th1 and Th2 Cytokine Profiles in Malignant Pleural Effusion
Background: The alteration of Th1 and Th2 cytokine levels is the subject of controversy in pleural effusions caused by malignancy, a situation that favors a Th2 immune response. Objective: To examine the different levels of IL-4 and IL-10 (Th2 cytokines), and IL-2 and interferon-γ (IFN-γ) (Th1 cytokines) in malignant and non-malignant pleural effusions. Method: The cytokine levels in pleural fl...
متن کاملبررسی میزان آنزیم آدنوزین دآمیناز در انواع پلورال افیوژن لنفوسیتی در بیمارستانهای فیروزگر و رسول اکرم(ص)The Survey of ADA Level in Different Lymphocytic Pleural Effusions in Firoozgar and Rasoul-e-Akram Hospitals
Background & Aim: Adenosine deminase(ADA) can be used in the diagnosis of tuberculous pleural effusions. In countries with high prevalence of tuberculous pleural effusions, specificity and sensitivity for ADA test is high, therefore it is an integral part of a diagnostic workup of lymphocyte-rich exudative body fluids, and it is a cheap and economically cost-effective test. No study has bee...
متن کاملبررسی مقایسهای نتایج تشخیصی سیتولوژی و بیوپسی افیوژن بدخیم پلور در بیماران مراجعهکننده به بیمارستان شهید صدوقی یزد بین سالهای 1383 تا 1393
Introduction: Malignant pleural effusion is recognized as the second most common cause of exudative pleural effusion. Thoracentesis and cytological examinations are regarded as simple procedures that can be performed easier than biopsy presenting less pain and danger. Hence, this study aimed to compare the results of malignant pleural fluidcytology and pathology of effusions in order to determi...
متن کاملDIFFERENTIATION BETWEEN BENIGN, REACTIVE AND MALIGNANT CELLS IN SEROSAL BODY FLUIDS BY AgNOR STAINING
Argyrophilic nucleolar organizer regions (AgNORs) were determined in 94 pleural, pericardial and peritoneal effusions. The results were correlated with cytologic diagnosis to determine the diagnostic potential of this technique. Cytologically the number of normal, reactive and malignant effusions were 32, 28 and 34 respectively. The mean AgNOR counts for normal, reactive and malignant spec...
متن کاملManagement of pleural effusions in cancer of the breast.
To the Editor: In the article entitled "Management of Pleural Effusions in Breast Cancer" (Chest 7 5 : 5 1 5 3 , 1 9 7 9 ) , Lees and Hoy report their experience in treating pleural effusions associated with carcinoma of the breast. While their study is a retrospective analysis, the numbers are large, and their technique for instillation of sclerosing agents into the pleural space following dra...
متن کاملMalignant Pleural Effusion: Medical Approaches for Diagnosis and Management
Malignant pleural effusions (MPEs) are the second leading cause of exudative pleural effusions after parapneumonic effusions. In the vast majority of cases, a MPE signifies incurable disease associated with high morbidity and mortality. Considerable advances have been made for the diagnosis of MPEs, through the development of improved methods in the specialized cytological and imaging studies. ...
متن کامل